Nov8 - New Origin Labs

NOV8 TM

Traditional supplements feed your body raw materials and hope it can do the work. NOV8™ changes the equation. As the world’s first pathway-independent Nitric Oxide metabolite, it bypasses your body’s unpredictable enzyme conversions. Through patented bioconversion engineering, we deliver a stabilized, bio-active matrix that guarantees consistent, measurable vasodilation for elite performance and lifelong vascular health.

Engineered for unmatched potency at low doses. Clinical data confirms our stabilized metabolite matrix generates a cumulative Nitric Oxide release 2,500x greater than leading traditional precursor formulas.

Clinically
Validated

Patented
Bioconversion

Pathway
independent

Plant-based
source

Why Nitric Oxide (NO)
Needs Innovation

Traditional supplements (like L-Arginine) act as raw materials for a factory that is shutting down. They act as “precursors,” relying 100% on your body’s natural enzymes to convert them into Nitric Oxide. As these enzymes decline by ~50% after age 40, these supplements lose their ability to work.

Beetroot powders rely on a fragile chain of oral bacteria and stomach acid for activation. Everyday factors like using mouthwash, taking antibiotics, or having low stomach acid can destroy the specific bacteria needed to make these products work, rendering them useless.

Even under perfect conditions, precursor supplements generate only a short, weak burst of Nitric Oxide. They lack the stability to remain effective over time, requiring massive, impractical dosages to achieve even a fraction of the sustained vasodilation provided by a true metabolite.

Nitric Oxide (NO) Pathways

Pathway 1: The Nitric
Oxide Synthase
Pathway

This is the body’s primary engine for producing Nitric Oxide. It relies on a complex enzymatic process to convert L-arginine into active NO. While it operates at 100% capacity during our youth, producing roughly 1,000 µmol per day. This pathway experiences a severe, natural decline as we age due to oxidative stress and enzymatic breakdown.

Pathway 2: The
Nitrate - Nitrite
Reductase
Pathway

Acting as an auxiliary backup system, this secondary pathway converts dietary nitrates (like those found in leafy greens) into Nitric Oxide. However, it is highly fragile and inefficient. It produces significantly less NO (only ~100 µmol per day) and is strictly dependent on a perfectly balanced oral microbiome and specific reductase enzymes to function.

The NOV8 Innovation

The Metabolite Revolution

We stopped asking the body to do the work. Instead of providing ‘raw materials’ (precursors) that require complex enzymatic conversion, NOV8™ utilizes a patented Bioconversion process. We ferment nitrate-rich botanicals into a stabilized, pre-converted Nitric Oxide Metabolite Matrix, essentially creating the ‘finished product’ before it ever enters your system.

This bypasses the biological bottlenecks of aging entirely. Because it is a finished metabolite, NOV8™ does not rely on your oral microbiome or declining enzymes to work. It activates immediately in the stomach, delivering a consistent, pathway-independent surge of Nitric Oxide that is 2,500x more potent than standard precursor supplements.

NEW ORIGIN LAB

The World’s First Pathway-Independent Nitric Oxide Solution.

How It Works

Sourcing Nitrate-Rich Botanicals

The process begins with nature. We source a specific, highly potent complex of nitrate-rich vegetables, including garlic, lettuce, and cabbage. Rather than relying on a single, synthetic compound, we harness the full biological potential of these natural precursors to serve as the foundation for our bio-engineering process.

Patented Bioconversion Process

This is where traditional supplementation ends and biotechnology begins. We subject the raw botanical extracts to our proprietary, patented fermentation process. This advanced bioconversion does the metabolic heavy lifting outside of your body, pre-converting the raw plant nitrates into an active, ready-to-use form.

Pathway-Independent Delivery

Why Pathway Independence Matters With Age

The "Danger Zone" of Aging

Clinical research confirms a precipitous drop in Nitric Oxide availability as we age. While your body’s natural production remains stable in youth, it enters a critical “Danger Zone” around age 40. By this stage, the primary endothelial pathway degrades, causing production to plummet by up to 50% creating a severe deficit that a healthy diet alone often cannot bridge.

The Root Cause: Enzyme Failure

As we age, a buildup of oxidative stress, lifestyle factors, and genetics directly impairs the Nitric Oxide Synthase (NOS) enzyme. The NOS enzyme’s ability to produce NO sharply declines, even though our bodies typically have enough naturally available Arginine waiting for conversion. Because the enzymatic “factory” is broken, feeding it more raw precursor supplements will not fix the deficit.

The Metabolite Bypass

To restore optimal cardiovascular health, we must stop relying on degraded biological machinery. A Pathway-Independent solution bypasses the compromised NOS enzyme entirely. By delivering a stabilized, pre-converted Nitric Oxide metabolite directly into your system, we can restore youthful NO levels with absolute precision regardless of your biological age, genetics, or oxidative stress levels.